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Chirurgische en poliklinische toepassingen

Histoacryl® weefsellijm

Bekijk de voordelen en veelzijdige toepassingen van de verschillende soorten Histoacryl® weefsellijm. 

Histoacryl®

  • Steriele, vloeibare en topische weefsellijmen.
  • Beschikbaar in butyl en octyl varianten.
  • Geschikt voor het sluiten van huidwonden met minimale spanning.
  • Kan worden bewaard op kamertemperatuur.
  • Vormt een microbiolgische barrière tegen bacteriën.
  • Is gemakkelijk aan te brengen door ready-to-use flacon.

Bekijk de toepassingen van alle Histoacryl® weefsellijmen

Histoacryl®

The tissue adhesive Histoacryl® consists of monomeric n-butyl-2-cyanoacrylate, which polymerizes quickly in connection with tissue fluid.Histoacryl® is available in two colors:translucent, special for facial applicationblue, which enables an easy control over the quantity applied in different indications approved.Indication:Skin Closure: Closure of skin wounds without tension (including clean surgical incisions and incisions from minimally invasive surgery), and simple, thoroughly cleansed, trauma-induced lacerations.Sclerotherapy: Sclerotherapy of large esophageal or fundal varices.Mesh fixation: Fixation of hernia meshes, especially in inguinal hernia surgery.

Histoacryl® Octyl

Instruction for Use The incision or trauma site must be clean and dry before applyingadhesive. Ensure that the wound edges are easily approximated. (Fig. 1)Screw the Applicator Tip onto the threaded tube in a clockwise direction until the applicator is tight and seated on the tube. The applicator will puncture the foil membrane on the tube once seated and adhesive will be allowed to flow. (Fig. 2)Hold the Micro tube tip downwards, and the 1mm version horizontal. Gently squeeze the tube from the bottom until the adhesive becomes visible through the applicator device. Keep the device pointed away from the patient, until ready to apply the adhesive. (Fig. 3)While approximating skin edges, apply by squeezing the tube gently and continuously as you spread the adhesive back and forth over the wound site. Continue to hold the wound edges in approximation until the adhesive becomes tacky - typically less than 20 seconds. A smooth and even coat of adhesive is desirable. (Fig. 4)Once adhesive has completely polymerised (non-tacky) you may cover the site with a secondary bandage. If a secondary bandage is used, DO NOT apply to the adhesive area until it is completely tack free. Applying whilst tacky may result in adhesive removal when removing the secondary bandage and possibly dehiscence of the wound site. (Fig. 5)Discard adhesive device according to normal protocol after use. (Fig. 6)

Histoacryl® Flexible Pack

Histoacryl® Flexible is a sterile and liquid topical skin adhesive, consisting of n-butyl-2 cyanoacrylate and a softener to enhance flexibility. Its advanced formulation supports the closure of short and long incisions of up to 25 cm[1-3], making it suitable for use in a broad range of surgical procedures as well as in emergency care settings.It’s available in 2 versions:Blue version: For easy visual assessment of the layer that has been appliedClear Version: Specially designed for facial and cosmetic applications Histoacryl® Flexible may be used with an optional applicator tip intended to provide easy distribution of the adhesive over the wound, ensuring a precise & comfortable application.

Histoacryl® voor wondsluiting

Weefsellijm voor het sluiten van chirurgische incisies en eenvoudige door trauma veroorzaakte snijwonden die grondig zijn gereinigd. Histoacryl® Flexible is zeer geschikt voor het sluiten van langere wonden die om meer flexibiliteit vragen en krachtige wondondersteuning nodig hebben. Histoacryl® Octyl is een steriele vloeibare variant die gemakkelijk is aan te brengen door verhoogde viscositeit en snelle polymerisatie in 30 seconde. [1-3]

Histoacryl® voor meshfixatie

Weefsellijm voor atraumatische meshfixatie, voornamelijk bij liesbreukchirurgie. Gemakkelijke applicatie met Histoacryl® LapFix. [12-17]

Histoacryl® voor sclerotherapie

Weefsellijm geschikt voor sclerotherapie van verwijde aderen in de slokdarm en submucosale aders in de slijmvlieslaag van de maagwand. [5-11] Sclerotherapie is het inspuiten van een vloeistof in het bloedvat waardoor dit dichtgaat.

Endoscopische techniek met Histoacryl® voor de behandeling van bloedende maagvarices.

Prof. Cárdenas biedt waardevolle inzichten en expertise op dit gebied en geeft een uitgebreid overzicht van de voorbereiding en toepassing van deze techniek.

Case Report: management of gastric varices

In deze video laat Prof. Cárdenas zien hoe de behandeling met Histoacryl® succesvol is uitgevoerd bij een patiënt met maagvarices.

Informatie

  • Onepager Histoacryl® assortiment

    Weefsellijm voor chirurgische en poliklinische toepassingen

    pdf, 1.6 MB

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  • Onepager Histoacryl® patiënteninformatie

    Alles wat je wil weten na behandeling met Histoacryl® huidlijm

    pdf, 1.4 MB

    download Download

  • Certificaat Histoacryl® superheld jongen

    Kleurplaat

    pdf, 550.1 KB

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  • Certificaat Histoacryl® superheld meisje

    Kleurplaat

    pdf, 553.4 KB

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Skin closure:

1) Elmasalme FN, Matbouli SA, Zuberi MS. Use of tissue adhesive in the closure of small incisions and lacerations. J Pediatr Surg. (1995) 30:6 (837-8).

Surgical wounds:

2) Dumville JC, Coulthard P, Worthington HV, Riley P, Patel N, Darcey J, Esposito M, van der Elst M, van Waes OJ. Tissue adhesives for closure of surgical incisions. Cochrane Database Syst Rev. (2014) Nov 28;(11)

3) Yulevich A, Cohen Z, Mares AJ. Use of N-Butyl-2-Cyanoacrylate (Histoacryl®) in Closure of Thoracoscopic an Laparoscopic Surgical Wounds in Children. Pediatric Endosurg. (1998) 2:1 (31-4).

Microbiologic barrier:

4) Data on file, mdt medical device testing GmbH report / Project 12m020 / Determination of Microbiological Barrier Properties of Two Topical Skin Adhesives.

Sclerotherapy:

5) Feretis C, Dimopoulos C, Benakis P, Kalliakmanis B, Apostolidis N. N-butyl-2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotherapy alone in the treatment of bleeding esophageal varices: a randomized prospective study. Endoscopy. (1995) 27:5 (355-7).

6) Kozieł S, Kobryń K, Paluszkiewicz R, Krawczyk M, Wróblewski T. Endoscopic treatment of gastric varices bleeding with the use of n-butyl-2 cyanoacrylate. Prz Gastroenterol (2015) 10:4 (239–243).

7) Jang WS, Shin HP, Lee JI, Joo KR, Cha JM, Jeon JW, Lim JU. Proton pump inhibitor administration delays rebleeding after endoscopic gastric variceal obturation. World journal of Gastroenterology (2014) 20:45 (17127-17131).

8) Prachayakul V, Aswakul P, Chantarojanasiri T, Leelakusolvong S. Factors influencing clinical outcomes of Histoacrylglue injection-treated gastric variceal hemorrhage. World J Gastroenterol. (2013) 19:15 (2379–2387).

9) Lo GH, Lin CW, Perng DS, Chang CY, Lee CT, Hsu CY, Wang HM, Lin HC. A retrospective comparative study of histoacryl injection and banding ligation in the treatment of acute type 1 gastric variceal hemorrhage. Scand J Gastroenterol. (2013) 48:10 (1198-204).

10) Feretis C, Dimopoulos C, Benakis P, Kalliakmanis B, Apostolidis N. N-butyl-2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotherapy alone in the treatment of bleeding esophageal varices: a randomized prospective study. Endoscopy. (1995) 27:5 (355-7).

11) Tan PC, Hou MC, Lin HC, Liu TT, Lee FY, Chang FY, Lee SD. A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligation. Hepatology. (2006) 43:4 (690-7).

Mesh fixation:

12) Hoyuela C, Juvany M, Carvajal F, Veres A, Troyano D, Trias M, Martrat A, Ardid J, Obiols J, López-Cano M. Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair. Br J Surg. (2017) 104:6 (688-694).

13) Hoyuela C, Juvany M, Carvajal F, Veres A, Troyano D, Trias M, Martrat A, Ardid J, Obiols J, López-Cano M. Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair. Br J Surg. (2017) 104:6 (688-694).

14) Helbling C, Schlumpf R. Sutureless Lichtenstein: first results of a prospective randomized clinical trial. Hernia. (2003) 7:2 (80-4).

15) Kim-Fuchs C, Angst E, Vorburger S, Helbling C, Candinas D, Schlumpf R. Prospective randomized trial comparing sutured with sutureless mesh fixation for Lichtenstein hernia repair: long-term results. Hernia. (2012) 16:1 (21-7).

16) Testini M, Lissidini G, Poli E, Gurrado A, Lardo D, Piccinni G. A singlesurgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair. Can J Surg. (2010) 53:3 (155-60

17) Kukleta JF, Freytag C, Weber M. Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia. (2012) 16:2 (153–62).